Cryo-electron Microscopy Single-Particle Analysis
Cryo-EM SPA
Single Particle Analysis (SPA) is a powerful technique combined with Cryo-Electron Microscopy (Cryo-EM), used for high-resolution structure determination of protein samples.
Cryo-EM eliminates the need for complex crystallization processes, providing samples that closely resemble their physiological state and without limitations related to the molecular weight of the target protein.
Nanomega CryoAI can offer various services, including 2D classification, 3D structure reconstruction, antigen epitope mapping, and more, to meet the diverse needs of single particle analysis at different stages.
Cryo-EM SPA Applications
Nanomega CryoAI is capable of successfully applying CRYO-EM technology in various types of protein structure imaging tasks to resolve target structures. These include antibody-antigen complexes, GPCRs (G-protein-coupled receptors), ion channels, multi-protein complexes, membrane proteins, soluble proteins, as well as protein-nucleic acid complexes.
Technical Advantages
Application Scenarios
